Diafiltration is often perceived as a bottleneck in the purification process. The Cadence Inline Diafiltration system simplifies the process by eliminating the requirement for the recirculation and dilution procedures widely practiced with conventional TFF.

Diafiltration buffer is added to the inlet streams while permeate is removed through the ultrafiltration membrane so maintaining retentate volume.

Completely removes, replaces, or lowers the concentration of salts or solvents from solutions containing proteins, peptides, nucleic acids, and other biomolecules.

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