Patented Single Pass Tangential Flow Filtration (SPTFF) technology enables continuous concentration of the product. The Cadence Inline Concentrator eliminates the requirement for re-circulation typically required for TFF, reducing shear damage and processing time for the processing step and improving quality.

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Features and benefits

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Increase capacity and reduce costs

Cadence Inline Concentrator modules can help to eliminate or reduce the size of intermediate storage tanks and associated cleaning of tanks when used for in-process volume reduction before or after existing steps.

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Continuous Ready

The robust SPTFF enables the continuous concentration of product to enhance subsequent process steps.

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Quality Improvements

SPTFF minimizes product shear enhancing product quality.

Specifications

  • Cassette

    Cadence Inline Concentrator modules are provided assembled, ready to use, Delta regenerated cellulose membrane, 10 kD or 30 kD with polypropylene screen, white polyurethane encapsulant with white pigment (TiO₂), and medical grade silicone for the permeate seals.

  • Gaskets

    Medical grade, platinum cured silicone

  • Manifold Plates

    UHMW polyethylene

  • Tubing and Connectors

    T01/T02 - female luer connection and cap: Polypropylene T12 - MPC quick disconnect connector and plug: Polysulfone T06 - MPX quick disconnect connector and plug: Polysulfone

  • Maximum Pressure

    4.1 barg (60 psig)

  • Maximum Transmembrane Pressure (TMP)

    4.1 barg (60 psig)

  • Processing Temperature Range

    4 – 40 °C (freezing will damage module)

  • pH Range

    2 – 13

Download the full specification